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- Title
Epitope spreading and a varying but not disease-specific GAD65 antibody response in Type I diabetes. The Childhood Diabetes in Finland Study Group.
- Authors
Söhnlein, P; Müller, M; Syren, K; Hartmann, U; Böhm, B O; Meinck, H M; Knip, M; Akerblom, H K; Richter, W
- Abstract
The aim of this study was to analyse the conformational and linear epitope profiles of glutamic acid decarboxylase antibody (GAD65-ab)-positive sera to find disease-specific epitope profiles and to study, whether GAD65-ab epitope recognition changes or spreads during the prediabetic period and, thus, can provide markers to differentiate early from later stages of progression to diabetes.
- Publication
Diabetologia, 2000, Vol 43, Issue 2, p210
- ISSN
0012-186X
- Publication type
Journal Article
- DOI
10.1007/s001250050031