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Title: Enhanced fatty acid uptake in visceral adipose tissue is not reversed by weight loss in obese individuals with the metabolic syndrome.
Authors: Bucci, Marco; Karmi, Anna C; Iozzo, Patricia; Fielding, Barbara A; Viljanen, Antti; Badeau, Robert M; Borra, Ronald; Saunavaara, Virva; Pham, Tam; Hannukainen, Jarna C; Kalliokoski, Kari; Haaparanta-Solin, Merja; Viljanen, Tapio; Parkkola, Riitta; Frayn, Keith N; Nuutila, Pirjo
Abstract: Obesity causes an imbalance in fat mass distribution between visceral and subcutaneous adipose tissue (AT) depots. We tested the hypothesis that this relates to increased NEFA uptake between these depots in obese compared with healthy participants. Second, we hypothesised that a diet very low in energy (very low calorie diet [VLCD]) decreases fat mass in obese participants and that this is associated with the decline in NEFA uptake.
Publication: Diabetologia, 2015, Vol 58, Issue 1, p158
ISSN: 1432-0428
Publication type: Journal Article
DOI: 10.1007/s00125-014-3402-x

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Enhanced fatty acid uptake in visceral adipose tissue is not reversed by weight loss in obese individuals with the metabolic syndrome.