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Title
Improvement in hepatic insulin sensitivity after Roux-en-Y gastric bypass in a rat model of obesity is partially mediated via hypothalamic insulin action.
Authors
Paranjape, S A; Chan, O; Zhu, W; Acharya, N K; Rogers, A M; Hajnal, A; Sherwin, R S
Abstract
Roux-en-Y gastric bypass (RYGB) surgery, an effective treatment for morbid obesity, commonly leads to near complete resolution of type 2 diabetes. The underlying mechanisms, however, remain unclear and factors other than weight loss alone may be involved.