We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse.
- Authors
Kuriya, G; Uchida, T; Akazawa, S; Kobayashi, M; Nakamura, K; Satoh, T; Horie, I; Kawasaki, E; Yamasaki, H; Yu, L; Iwakura, Y; Sasaki, H; Nagayama, Y; Kawakami, A; Abiru, N
- Abstract
T helper type (Th) 17 cells have been shown to play important roles in mouse models of several autoimmune diseases that have been classified as Th1 diseases. In the NOD mouse, the relevance of Th1 and Th17 is controversial, because single-cytokine-deficient NOD mice develop diabetes similarly to wild-type NOD mice.
- Publication
Diabetologia, 2013, Vol 56, Issue 8, p1773
- ISSN
1432-0428
- Publication type
Journal Article
- DOI
10.1007/s00125-013-2935-8