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- Title
Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1.
- Authors
Torekov, S S; Ma, L; Grarup, N; Hartmann, B; Hainerová, I A; Kielgast, U; Kissow, H; Rosenkilde, M; Lebl, J; Witte, D R; Jørgensen, T; Sandbaek, A; Lauritzen, T; Madsen, O D; Wang, J; Linneberg, A; Madsbad, S; Holst, J J; Hansen, T; Pedersen, O; GIANT Consortium
- Abstract
The glucagon gene (GCG) encodes several hormones important for energy metabolism: glucagon, oxyntomodulin and glucagon-like peptide (GLP)-1 and -2. Variants in GCG may associate with type 2 diabetes, obesity and/or related metabolic traits.
- Publication
Diabetologia, 2011, Vol 54, Issue 11, p2820
- ISSN
1432-0428
- Publication type
Journal Article
- DOI
10.1007/s00125-011-2265-7