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- Title
Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight.
- Authors
Andersson, E A; Pilgaard, K; Pisinger, C; Harder, M N; Grarup, N; Faerch, K; Poulsen, P; Witte, D R; Jørgensen, T; Vaag, A; Hansen, T; Pedersen, O
- Abstract
The fetal insulin hypothesis suggests that variation in the fetal genotype influencing insulin secretion or action may predispose to low birthweight and type 2 diabetes. We examined associations between 25 confirmed type 2 diabetes risk variants and birthweight in individuals from the Danish Inter99 population and in meta-analyses including Inter99 data and reported studies.
- Publication
Diabetologia, 2010, Vol 53, Issue 9, p1908
- ISSN
1432-0428
- Publication type
Journal Article
- DOI
10.1007/s00125-010-1790-0