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Title
The use of metformin in type 1 diabetes: a systematic review of efficacy.
Authors
Vella, S; Buetow, L; Royle, P; Livingstone, S; Colhoun, H M; Petrie, J R
Abstract
As adding metformin to insulin therapy has been advocated in type 1 diabetes, we conducted a systematic review of published clinical trials and clinical trial databases to assess the effects on HbA(1c), weight, insulin-dose requirement and adverse effects.