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Title
Is islet autoimmunity related to insulin sensitivity or body weight in children of parents with type 1 diabetes?
Authors
Winkler, C; Marienfeld, S; Zwilling, M; Bonifacio, E; Ziegler, A-G
Abstract
It has been suggested that metabolic demand and insulin resistance play a role in the development of type 1 diabetes, including the onset of autoimmunity. The aim of the present study was to determine whether insulin demand is increased in children with islet autoantibodies.