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Title
Assessing gene-treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program.
Authors
Franks, P W; Jablonski, K A; Delahanty, L M; McAteer, J B; Kahn, S E; Knowler, W C; Florez, J C; Diabetes Prevention Program Research Group
Abstract
The single nucleotide polymorphism (SNP) rs9939609 in the fat mass and obesity associated gene (FTO) and the rs7566605 SNP located 10 kb upstream of the insulin-induced gene 2 gene (INSIG2) have been proposed as risk factors for common obesity.