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- Title
Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia.
- Authors
Cani, P D; Neyrinck, A M; Fava, F; Knauf, C; Burcelin, R G; Tuohy, K M; Gibson, G R; Delzenne, N M
- Abstract
Recent evidence suggests that a particular gut microbial community may favour occurrence of the metabolic diseases. Recently, we reported that high-fat (HF) feeding was associated with higher endotoxaemia and lower Bifidobacterium species (spp.) caecal content in mice. We therefore tested whether restoration of the quantity of caecal Bifidobacterium spp. could modulate metabolic endotoxaemia, the inflammatory tone and the development of diabetes.
- Publication
Diabetologia, 2007, Vol 50, Issue 11, p2374
- ISSN
0012-186X
- Publication type
Journal Article
- DOI
10.1007/s00125-007-0791-0