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- Title
Upregulation of adiponectin receptor 1 and 2 mRNA and protein in adipose tissue and adipocytes in insulin-resistant women with polycystic ovary syndrome.
- Authors
Tan, B K; Chen, J; Digby, J E; Keay, S D; Kennedy, C R; Randeva, H S
- Abstract
Polycystic ovary syndrome (PCOS) is a multifaceted metabolic disease linked with insulin resistance (IR) and obesity. Adiponectin, which is lower in IR states, exerts its glucose-lowering and anti-inflammatory effects by activating two receptors, ADIPOR1 and ADIPOR2. There are no data on the relative expression of these receptors in adipose tissue of PCOS women.
- Publication
Diabetologia, 2006, Vol 49, Issue 11, p2723
- ISSN
0012-186X
- Publication type
Journal Article
- DOI
10.1007/s00125-006-0419-9