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Title
Proinsulin levels and the proinsulin:c-peptide ratio complement autoantibody measurement for predicting type 1 diabetes.
Authors
Truyen, I; De Pauw, P; Jørgensen, P N; Van Schravendijk, C; Ubani, O; Decochez, K; Vandemeulebroucke, E; Weets, I; Mao, R; Pipeleers, D G; Gorus, F K; Belgian Diabetes Registry
Abstract
We investigated whether random proinsulin levels and proinsulin:C-peptide ratio (PI:C) complement immune and genetic markers for identifying relatives at high risk of type 1 diabetes.