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- Title
Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?
- Authors
Meier, J J; Bhushan, A; Butler, A E; Rizza, R A; Butler, P C
- Abstract
Type 1 diabetes is widely held to result from an irreversible loss of insulin-secreting beta cells. However, insulin secretion is detectable in some people with long-standing type 1 diabetes, indicating either a small population of surviving beta cells or continued renewal of beta cells subject to ongoing autoimmune destruction. The aim of the present study was to evaluate these possibilities.
- Publication
Diabetologia, 2005, Vol 48, Issue 11, p2221
- ISSN
0012-186X
- Publication type
Journal Article
- DOI
10.1007/s00125-005-1949-2