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- Title
Little evidence of transdifferentiation of bone marrow-derived cells into pancreatic beta cells.
- Authors
Choi, J B; Uchino, H; Azuma, K; Iwashita, N; Tanaka, Y; Mochizuki, H; Migita, M; Shimada, T; Kawamori, R; Watada, H
- Abstract
Bone marrow cells contain at least two distinct types of stem cells which are haematopoietic stem cells and mesenchymal stem cells. Both cells have the ability to differentiate into a variety of cell types derived from all three germ layers. Thus, bone marrow stem cells could possibly be used to generate new pancreatic beta cells for the treatment of diabetes. In this study, we investigated the feasibility of bone marrow-derived cells to differentiate into beta cells in pancreas.
- Publication
Diabetologia, 2003, Vol 46, Issue 10, p1366
- ISSN
0012-186X
- Publication type
Journal Article
- DOI
10.1007/s00125-003-1182-9