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- Title
Peptide therapy for Type I diabetes: the immunological homunculus and the rationale for vaccination.
- Authors
Cohen, I R
- Abstract
The autoimmune process that produces Type I (insulin-dependent) diabetes mellitus seems to respond favourably to therapeutic vaccination with a peptide of the 60 kDa heat shock protein. This article is a personal review of the observations and the thinking that gave rise to the idea of therapeutic peptide vaccination. The rationale for vaccination therapy is compared to other approaches aimed at specific immunological treatment for autoimmune disease.
- Publication
Diabetologia, 2002, Vol 45, Issue 10, p1468
- ISSN
0012-186X
- Publication type
Journal Article
- DOI
10.1007/s00125-002-0937-z