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- Title
Anwendungsmöglichkeiten neuer Stammzellquellen in der Neurologie.
- Authors
Hermann, A.; Storch, A.; Liebau, S.
- Abstract
Stem cells provide broad possibilities in modern science and medicine. This counts not only for investigations of developmental aspects but also for cell-based therapies, pharmacotoxicological testing and improvements in personalized medicine. The recent described techniques of induced pluripotent stem cells, directly induced neural stem cells and directly induced neurons are a major step forward by providing new possibilities for research on neurological diseases. Nevertheless, a variety of questions remain open regarding stem cell-based therapeutic strategies including tumorigenicity and phenotypical stability in the receptor brain. The major hope is that the new stem cell-based neural cell systems will help to understand the pathophysiology of neurodegenerative diseases. The future will show whether and how stem cells will lead to successful restorative therapies and/or to suitable cell models for neurological diseases.
- Publication
Der Nervenarzt, 2013, Vol 84, Issue 8, p943
- ISSN
0028-2804
- Publication type
Academic Journal
- DOI
10.1007/s00115-013-3753-4