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- Title
Membrane fusion: SNAREs and regulation.
- Authors
Malsam, J; Kreye, S; Söllner, T H
- Abstract
SNARE (SNAP receptor) proteins drive intracellular membrane fusion and contribute specificity to membrane trafficking. The formation of SNAREpins between membranes is spatially and temporally controlled by a network of sequentially acting accessory components. These regulators add an additional layer of specificity, arrest SNAREpin intermediates, lower the energy required for fusion, and couple membrane fusion to triggering signals. The functional activity of some of these regulators determines the plasticity of regulated exocytosis.
- Publication
Cellular and molecular life sciences : CMLS, 2008, Vol 65, Issue 18, p2814
- ISSN
1420-682X
- Publication type
Journal Article
- DOI
10.1007/s00018-008-8352-3