We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Biomedicine and Diseases: Review¶Assembling the human immunodeficiency virus type 1.
- Authors
Cimarelli, A.; Darlix, J. -.L.
- Abstract
Retroviral assembly proceeds through a series of concerted events that lead to the formation and release of infectious virion particles from the infected cell. Upon translation, structural proteins are targeted to the plasma membrane where they accumulate. There, the nascent particle forces the plasma membrane to form a bud, which pinches off releasing the virion particle from the cell. In this review we describe the molecular mechanisms now known to be behind the process of virion assembly. In particular, we focus on the human immunodeficiency virus type 1, the prototype member of the lentivirus subfamily of the Retroviridae.
- Publication
Cellular & Molecular Life Sciences, 2002, Vol 59, Issue 7, p1166
- ISSN
1420-682X
- Publication type
Academic Journal
- DOI
10.1007/s00018-002-8495-6