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- Title
Implementation of the standard strategy for identification of Ig/TCR targets for minimal residual disease diagnostics in B-cell precursor ALL pediatric patients: Polish experience.
- Authors
Dawidowska, Małgorzata; Jółkowska, Justyna; Szczepański, Tomasz; Derwich, Katarzyna; Wachowiak, Jacek; Witt, Michał
- Abstract
Minimal residual disease (MRD), detected based on immunoglobulin and T-cell receptor (Ig/TCR) gene rearrangements as markers of residual leukemic cells, is currently the most reliable prognostic factor in acute lymphoblastic leukemia (ALL). A feasibility study is presented of the standard strategy for the identification of Ig/TCR targets for MRD diagnostics in Polish ALL patients by identifying Ig/TCR gene rearrangement pattern using standard primer sets and protocols.
- Publication
Archivum immunologiae et therapiae experimentalis, 2008, Vol 56, Issue 6, p409
- ISSN
1661-4917
- Publication type
Journal Article
- DOI
10.1007/s00005-008-0045-y