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- Title
A randomised controlled trial of delayed cord clamping in very low birth weight preterm infants.
- Authors
Rabe, H; Wacker, A; Hülskamp, G; Hörnig-Franz, I; Schulze-Everding, A; Harms, E; Cirkel, U; Louwen, F; Witteler, R; Schneider, H P
- Abstract
This study was carried out to assess the feasibility of late cord clamping of 45 s in preterm infants delivered mainly by caesarean section and the effects on postpartal adaptation and anaemia of prematurity. Prior to delivery, 40 infants of < 33 gestational weeks were randomised to either 20 s or 45 s of late cord clamping. After the first shoulder was delivered, oxytocin was given intravenously to the mother in order to enhance placento-fetal transfusion while the infant was held below the level of the placenta. The 20 infants in group 1 (20 s) had a mean birth weight of 1070 g and a mean gestational age of 29 + 4/7 weeks versus 1190 g and 30 weeks in group 2 (45 s). On day 42 of life there were ten infants without transfusions in group 2 versus three in group 1 (P < 0.05). Out of the 20 infants in group 1, 19 and 15/19 in group 2 were delivered by caesarean section. There were no significant differences in Apgar scores, temperature on admission, heart rate, blood pressure and requirements for artificial ventilation.
- Publication
European journal of pediatrics, 2000, Vol 159, Issue 10, p775
- ISSN
0340-6199
- Publication type
Journal Article
- DOI
10.1007/pl00008345