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- Title
The relationship between lesion and normal appearing brain tissue abnormalities in early relapsing remitting multiple sclerosis.
- Authors
Griffin, Colette M; Chard, Declan T; Parker, Geoff J M; Barker, Gareth J; Thompson, Alan J; Miller, David H
- Abstract
In multiple sclerosis (MS), pathological changes have been found both in macroscopic lesions and normal appearing tissue. Magnetisation transfer ratio (MTR) and T1 relaxation time are abnormal in normal appearing tissues in established MS. This study used these MR techniques in early MS to study normal appearing tissues and lesions. The purpose was to determine whether abnormalities are already detectable in normal appearing tissues in early MS, and if so how they correlate with lesion characteristics.
- Publication
Journal of neurology, 2002, Vol 249, Issue 2, p193
- ISSN
0340-5354
- Publication type
Journal Article
- DOI
10.1007/pl00007864