We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Myelin basic protein and multiple sclerosis.
- Authors
Whitaker, J N
- Abstract
Myelin basic protein (BP) has the capacity to induce experimental allergic encephalomyelitis (EAE) in animals as well as to prevent and suppress EAE. Immunoreactive BP or BP fragments appear in cerebrospinal fluid (CSF) in persons with multiple sclerosis in acute disease periods and in individuals with acute damage to central nervous system myelin. Humoral and cellular immune responses, especially in the CSF, may occur but are of uncertain effect in the etiology and pathogenesis of MS. Attempts to use BP to suppress MS have disclosed no therapeutic benefit.
- Publication
Italian journal of neurological sciences, 1983, Vol 4, Issue 2, p153
- ISSN
0392-0461
- Publication type
Journal Article
- DOI
10.1007/BF02043898