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- Title
Two-stage meta-analysis of survival data from individual participants using percentile ratios.
- Authors
Barrett, Jessica K; Farewell, Vern T; Siannis, Fotios; Tierney, Jayne; Higgins, Julian P T
- Abstract
Methods for individual participant data meta-analysis of survival outcomes commonly focus on the hazard ratio as a measure of treatment effect. Recently, Siannis et al. (2010, Statistics in Medicine 29:3030-3045) proposed the use of percentile ratios as an alternative to hazard ratios. We describe a novel two-stage method for the meta-analysis of percentile ratios that avoids distributional assumptions at the study level.
- Publication
Statistics in medicine, 2012, Vol 31, Issue 30, p4296
- ISSN
1097-0258
- Publication type
Journal Article
- DOI
10.1002/sim.5516