We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Overexpression of the sterol 14α-demethylase gene (MgCYP51) in Mycosphaerella graminicola isolates confers a novel azole fungicide sensitivity phenotype.
- Authors
Cools, Hans J; Bayon, Carlos; Atkins, Sarah; Lucas, John A; Fraaije, Bart A
- Abstract
The recent evolution towards resistance to azole fungicides in European populations of the wheat pathogen Mycosphaerella graminicola has been caused by the progressive accumulation of mutations in MgCYP51 gene, encoding the azole target sterol 14α-demethylase. Particular combinations of mutations have been shown specifically to affect the interaction of the MgCYP51 protein with different members of the azole class. Although additional mechanisms, including increased MgCYP51 expression and enhanced active efflux, have been proposed, the genetic changes underlying these mechanisms are unknown.
- Publication
Pest management science, 2012, Vol 68, Issue 7, p1034
- ISSN
1526-4998
- Publication type
Journal Article
- DOI
10.1002/ps.3263