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- Title
Interleukin-17 promotes development of castration-resistant prostate cancer potentially through creating an immunotolerant and pro-angiogenic tumor microenvironment.
- Authors
Zhang, Qiuyang; Liu, Sen; Zhang, Qingsong; Xiong, Zhenggang; Wang, Alun R; Myers, Leann; Melamed, Jonathan; Tang, Wendell W; You, Zongbing
- Abstract
Interleukin-17 (IL-17) has been demonstrated to promote formation and growth of hormone-naïve prostate adenocarcinoma in mice. IL-17's role in development of castration-resistant prostate cancer is unknown. In the present study, we investigated IL-17's role in castration-resistant prostate cancer in a mouse model.
- Publication
The Prostate, 2014, Vol 74, Issue 8, p869
- ISSN
1097-0045
- Publication type
Journal Article
- DOI
10.1002/pros.22805