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- Title
Cyclin D1 (CCND1) expression is involved in estrogen receptor beta (ERβ) in human prostate cancer.
- Authors
Nakamura, Yasuhiro; Felizola, Saulo J A; Kurotaki, Yumi; Fujishima, Fumiyoshi; McNamara, Keely M; Suzuki, Takashi; Arai, Yoichi; Sasano, Hironobu
- Abstract
Estrogen receptor beta (ERβ) has been demonstrated to be expressed in prostate carcinoma cells and estrogen signals through ERβ to act as a tumor suppressor in prostate cancer patients. ERβ is thought to regulate the cell cycle of prostate carcinoma cells by controlling the expression of cell cycle regulators including cyclin D1 (CCND1). This interaction is of particular interest as CCND1 has been implicated in the development of prostate cancer.
- Publication
The Prostate, 2013, Vol 73, Issue 6, p590
- ISSN
1097-0045
- Publication type
Journal Article
- DOI
10.1002/pros.22599