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- Title
PSA regulates androgen receptor expression in prostate cancer cells.
- Authors
Saxena, Parmita; Trerotola, Marco; Wang, Tao; Li, Jing; Sayeed, Aejaz; Vanoudenhove, Jennifer; Adams, Dave S; Fitzgerald, Thomas J; Altieri, Dario C; Languino, Lucia R
- Abstract
Prostate-specific antigen (PSA) is a pivotal downstream target gene of the androgen receptor (AR), and a serum biomarker to monitor prostate cancer (PrCa) progression. It has been reported that PSA transactivates AR, but the mechanistic requirements of this response have not been investigated.
- Publication
The Prostate, 2012, Vol 72, Issue 7, p769
- ISSN
1097-0045
- Publication type
Journal Article
- DOI
10.1002/pros.21482