We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan of 762 prostate cancer families collected by the ICPCG.
- Authors
Lu, Lingyi; Cancel-Tassin, Geraldine; Valeri, Antoine; Cussenot, Olivier; Lange, Ethan M; Cooney, Kathleen A; Farnham, James M; Camp, Nicola J; Cannon-Albright, Lisa A; Tammela, Teuvo L J; Schleutker, Johanna; Hoegel, Josef; Herkommer, Kathleen; Maier, Christiane; Vogel, Walther; Wiklund, Fredrik; Emanuelsson, Monica; Grönberg, Henrik; Wiley, Kathleen E; Isaacs, Sarah D; Walsh, Patrick C; Helfand, Brian T; Kan, Donghui; Catalona, William J; Stanford, Janet L; FitzGerald, Liesel M; Johanneson, Bo; Deutsch, Kerry; McIntosh, Laura; Ostrander, Elaine A; Thibodeau, Stephen N; McDonnell, Shannon K; Hebbring, Scott; Schaid, Daniel J; Whittemore, Alice S; Oakley-Girvan, Ingrid; Hsieh, Chih-Lin; Powell, Isaac; Bailey-Wilson, Joan E; Cropp, Cheryl D; Simpson, Claire; Carpten, John D; Seminara, Daniela; Zheng, S Lilly; Xu, Jianfen; Giles, Graham G; Severi, Gianluca; Hopper, John L; English, Dallas R; Foulkes, William D; Maehle, Lovise; Moller, Pal; Badzioch, Michael D; Edwards, Steve; Guy, Michelle; Eeles, Ros; Easton, Douglas; Isaacs, William B; International Consortium for Prostate Cancer Genetics
- Abstract
In spite of intensive efforts, understanding of the genetic aspects of familial prostate cancer (PC) remains largely incomplete. In a previous microsatellite-based linkage scan of 1,233 PC families, we identified suggestive evidence for linkage (i.e., LOD ≥ 1.86) at 5q12, 15q11, 17q21, 22q12, and two loci on 8p, with additional regions implicated in subsets of families defined by age at diagnosis, disease aggressiveness, or number of affected members.
- Publication
The Prostate, 2012, Vol 72, Issue 4, p410
- ISSN
1097-0045
- Publication type
Journal Article
- DOI
10.1002/pros.21443