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- Title
Serum fibrinogen alpha C-chain 5.9 kDa fragment as a biomarker for early detection of hepatic fibrosis related to hepatitis C virus.
- Authors
Sogawa, Kazuyuki; Noda, Kenta; Umemura, Hiroshi; Seimiya, Masanori; Kuga, Takahisa; Tomonaga, Takeshi; Nishimura, Motoi; Kanai, Fumihiko; Imazeki, Fumio; Takizawa, Hirotaka; Yoneda, Masato; Nakajima, Atsushi; Tsutsumi, Mikihiro; Yokosuka, Osamu; Nomura, Fumio
- Abstract
Clinical application of biomarker candidates discovered by proteomic analysis is challenging. The purpose of this study was to standardize preanalytical conditions for measurement of serum levels of fibrinogen alpha C-chain 5.9 kDa fragment (FIC 5.9) and to test the diagnostic value of this peptide for detection of early hepatic fibrosis in patients with hepatitis C virus (HCV)-related chronic hepatitis.
- Publication
Proteomics. Clinical applications, 2013, Vol 7, Issue 5-6, p424
- ISSN
1862-8354
- Publication type
Journal Article
- DOI
10.1002/prca.201200094