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- Title
Open-label, follow-on study of azithromycin in pediatric patients with CF uninfected with Pseudomonas aeruginosa.
- Authors
Saiman, Lisa; Mayer-Hamblett, Nicole; Anstead, Michael; Lands, Larry C; Kloster, Margaret; Goss, Christopher H; Rose, Lynn M; Burns, Jane L; Marshall, Bruce C; Ratjen, Felix; AZ0004 Macrolide Study Team
- Abstract
We previously performed a randomized placebo-controlled trial to examine the effects of azithromycin in children and adolescents 6-18 years of age with cystic fibrosis uninfected with Pseudomononas aeruginosa and demonstrated that while azithromycin did not acutely improve pulmonary function, azithromycin-reduced pulmonary exacerbations, decreased the initiation of new oral antibiotics, and improved weight gain. We now report the results of the open-label, follow-on study to assess durability of response to azithromycin and continued safety and tolerability.
- Publication
Pediatric pulmonology, 2012, Vol 47, Issue 7, p641
- ISSN
1099-0496
- Publication type
Journal Article
- DOI
10.1002/ppul.21601