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Title
Neoplastic causes of abnormal puberty.
Authors
Wendt, Susanne; Shelso, John; Wright, Karen; Furman, Wayne
Abstract
Neoplasm-related precocious puberty (PP) is a rare presenting feature of childhood cancer. Moreover, evaluation of suspected PP in a child is complex, and cancer is often not considered. We characterized the clinicopathologic features of patients presenting with PP at a large pediatric cancer center, reviewed the relevant literature, and developed an algorithm for the diagnostic work-up of these patients.