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- Title
Durable immune response to inactivated H1N1 vaccine is less likely in children with sickle cell anemia receiving chronic transfusions.
- Authors
Purohit, Saroj; Alvarez, Ofelia; O'Brien, Robert; Andreansky, Samita
- Abstract
Defects in the immune system may affect vaccine responsiveness. Because of the splenic hypofunction and abnormal opsonic activity, it was unknown whether patients with sickle cell disease (SCD) would respond appropriately to H1N1 vaccination. The objective of this study was to assess seroprotective post-vaccine H1N1 antibody response in children with SCD.
- Publication
Pediatric blood & cancer, 2012, Vol 59, Issue 7, p1280
- ISSN
1545-5017
- Publication type
Journal Article
- DOI
10.1002/pbc.24206