Zage, Peter E; Nolo, Riitta; Fang, Wendy; Stewart, John; Garcia-Manero, Guillermo; Zweidler-McKay, Patrick A
Abstract
Notch pathway signaling has critical roles in differentiation, proliferation, and survival, and has oncogenic or tumor suppressor effects in a variety of malignancies. The goal of this study was to evaluate the effects of Notch activation on human neuroblastoma cells.