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- Title
Antihyperglycemic effect of equol, a daidzein derivative, in cultured L6 myocytes and ob/ob mice.
- Authors
Cheong, Sun Hee; Furuhashi, Keisuke; Ito, Katsuki; Nagaoka, Masato; Yonezawa, Takayuki; Miura, Yutaka; Yagasaki, Kazumi
- Abstract
Molecular mechanisms for the potential antihyperglycemic effect of equol remain to be elucidated. In this study, we investigated the in vitro effect of equol on glucose uptake, AMP-activated protein kinase (AMPK) phosphorylation, and glucose transporter 4 (GLUT4) translocation to plasma membrane in L6 myocytes, and its in vivo antihyperglycemic effect in obese-diabetic model ob/ob mice.
- Publication
Molecular nutrition & food research, 2014, Vol 58, Issue 2, p267
- ISSN
1613-4133
- Publication type
Journal Article
- DOI
10.1002/mnfr.201300272