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- Title
Green tea epigallocatechin-3-gallate (EGCG) promotes neural progenitor cell proliferation and sonic hedgehog pathway activation during adult hippocampal neurogenesis.
- Authors
Wang, Yanyan; Li, Maoquan; Xu, Xueqing; Song, Min; Tao, Huansheng; Bai, Yun
- Abstract
Adult hippocampal neurogenesis is a lifelong feature of brain plasticity that appears to be critically involved in adult brain function and neurological disease. Recent studies suggest that (-)-epigallocatechin-3-gallate (EGCG), which is the main polyphenolic constituent of green tea, may be used for the prevention and treatment of various neurodegenerative diseases. We hypothesized that EGCG promotes adult neurogenesis, which may be beneficial to hippocampus-dependent learning and memory.
- Publication
Molecular nutrition & food research, 2012, Vol 56, Issue 8, p1292
- ISSN
1613-4133
- Publication type
Journal Article
- DOI
10.1002/mnfr.201200035