We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The role of SCARB2 as susceptibility factor in Parkinson's disease.
- Authors
Hopfner, Franziska; Schulte, Eva C; Mollenhauer, Brit; Bereznai, Benjamin; Knauf, Franziska; Lichtner, Peter; Zimprich, Alexander; Haubenberger, Dietrich; Pirker, Walter; Brücke, Thomas; Peters, Annette; Gieger, Christian; Kuhlenbäumer, Gregor; Trenkwalder, Claudia; Winkelmann, Juliane
- Abstract
Genetic variation in the glucocerebrosidase (GBA) gene is strongly associated with Parkinson's disease (PD). Transport of glucocerebrosidase to the lysosome involves the protein encoded by the SCARB2 gene. An association between the common SNP rs6812193, upstream of SCARB2, and PD has been reported previously. The role of exonic variants in the SCARB2 gene in PD has not been examined.
- Publication
Movement disorders : official journal of the Movement Disorder Society, 2013, Vol 28, Issue 4, p538
- ISSN
1531-8257
- Publication type
Journal Article
- DOI
10.1002/mds.25349