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- Title
Common genetic variants in the 8q24 region and risk of papillary thyroid cancer.
- Authors
Neta, Gila; Yu, Chu-Ling; Brenner, Alina; Gu, Fangyi; Hutchinson, Amy; Pfeiffer, Ruth; Sturgis, Erich M; Xu, Li; Linet, Martha S; Alexander, Bruce H; Chanock, Stephen; Sigurdson, Alice J
- Abstract
Single nucleotide polymorphisms (SNPs) in the 8q24 chromosomal region identified from genome-wide scans have been associated with the risk of several cancers, including breast (rs1562430), prostate (rs1447295), and colon (rs6983267). A genome-wide scan in 26 families with papillary thyroid cancer (PTC) also found susceptibility loci in 8q24, supporting a closer evaluation of this chromosomal region in relation to the risk of sporadic PTC.
- Publication
The Laryngoscope, 2012, Vol 122, Issue 5, p1040
- ISSN
1531-4995
- Publication type
Journal Article
- DOI
10.1002/lary.23209