To evaluate the neurochemical changes associated with hypomyelination, especially to clarify whether increased total N-acetylaspartate (tNAA) with decreased choline (Cho) observed in the thalamus of msd mice with the plp1 mutation is a common finding for hypomyelinating disorders.
Publication
Journal of magnetic resonance imaging : JMRI, 2014, Vol 39, Issue 6, p1550