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- Title
SWI/SNF: the crossroads where extracellular signaling pathways meet chromatin.
- Authors
Simone, Cristiano
- Abstract
The coordinated expression of the genome in response to extracellular cues is ensured by enzymatic cascades signaling to the nucleus. These pathways generate chromatin modifications at specific loci controlling the transcription of signal-dependent and tissue-specific genes. The SWI/SNF chromatin remodeling complex offers the ideal surface for integrating these signals in the execution of diverse or even opposite biological programs.
- Publication
Journal of cellular physiology, 2006, Vol 207, Issue 2, p309
- ISSN
0021-9541
- Publication type
Journal Article
- DOI
10.1002/jcp.20514