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- Title
Successful collection and engraftment of autologous peripheral blood progenitor cells in poorly mobilized patients receiving high-dose granulocyte colony-stimulating factor.
- Authors
Cooper, Dennis L; Proytcheva, Maria; Medoff, Erin; Seropian, Stuart E; Snyder, Edward L; Krause, Diane S; Wu, Yanyun
- Abstract
Granulocyte Colony-Stimulating Factor (G-CSF) alone or in conjunction with chemotherapy is commonly used to mobilize hematopoietic progenitor cells (HPC) into peripheral blood for progenitor cell harvest for autologous HPC transplantation. However, in up to 30% of patients, HPC are not effectively mobilized. In this study, we report the efficacy and safety profiles of a mobilization strategy using high-dose (up to 36 μg/kg) G-CSF in poorly mobilized patients.
- Publication
Journal of clinical apheresis, 2012, Vol 27, Issue 5, p235
- ISSN
1098-1101
- Publication type
Journal Article
- DOI
10.1002/jca.21232