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- Title
The effect of catechol-O-methyltransferase polymorphisms on pain is modified by depressive symptoms.
- Authors
Schwahn, C; Grabe, H J; Meyer zu Schwabedissen, H; Teumer, A; Schmidt, C O; Brinkman, C; Kocher, T; Nauck, M; Völzke, H; Biffar, R; Bernhardt, O
- Abstract
Variations within the catechol-O-methyltransferase (COMT) gene have been associated with pain severity in temporomandibular disorders (TMDs). Psychological factors such as personal conflicts, life stress and depression, are well known to be associated with onset, severity and chronicity of pain disorders.
- Publication
European journal of pain (London, England), 2012, Vol 16, Issue 6, p878
- ISSN
1532-2149
- Publication type
Journal Article
- DOI
10.1002/j.1532-2149.2011.00067.x