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- Title
Insulin-like growth factor-1 receptor inhibitor, AMG-479, in cetuximab-refractory head and neck squamous cell carcinoma.
- Authors
Chung, Christine H; Pohlmann, Paula R; Rothenberg, Mace L; Burkey, Brian B; Parker, Joel; Palka, Kevin; Aulino, Joseph; Puzanov, Igor; Murphy, Barbara
- Abstract
Recurrent head and neck squamous cell carcinoma (HNSCC) remains a difficult cancer to treat. Here, we describe a patient with HNSCC who had complete response to methotrexate (MTX) after progressing on multiple cytotoxic agents, cetuximab, and AMG-479 (monoclonal antibody against insulin-like growth factor-1 receptor [IGF-1R]).
- Publication
Head & neck, 2011, Vol 33, Issue 12, p1804
- ISSN
1097-0347
- Publication type
Journal Article
- DOI
10.1002/hed.21478