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- Title
Higher laryngeal preservation rate after CO<sub>2</sub> laser surgery compared with radiotherapy in T1a glottic laryngeal carcinoma.
- Authors
Schrijvers, Michiel L.; Van Riel, Eva L.; Langendijk, Johannes A.; Dikkers, Frederik G.; Schuuring, Ed; Van der Wal, Jacqueline E.; Van der Laan, Bernard F. A. M.
- Abstract
Background. Clinical outcome of endoscopic CO2 laser surgery and radiotherapy in early-stage glottic laryngeal carcinoma is difficult to compare because of differences in treatment selection and patient groups. Therefore, we compared local control, overall survival, and laryngeal preservation in a homogenous group of patients with T1a glottic carcinoma with normal/diminished mucosal wave treated with either CO2 laser surgery or radiotherapy. Methods. Retrospective survival analysis was performed on 100 patients with T1a glottic carcinoma treated with CO2 laser surgery (n = 49) or radiotherapy (n = 51), diagnosed at the University Medical Center Groningen between 1990 and 2004. Results. No significant differences in local control and overall survival were found. Ultimate 5-year laryngeal preservation was significantly better in the CO2 laser surgery group (95% vs 77%, p = .043). Conclusion. Patients with T1a glottic carcinoma with normal/diminished mucosal wave treated with CO2 laser surgery had a significantly better laryngeal preservation rate than patients treated with radiotherapy. © 2009 Wiley Periodicals, Inc. Head Neck, 2009
- Publication
Head & Neck, 2009, Vol 31, Issue 6, p759
- ISSN
1043-3074
- Publication type
Academic Journal
- DOI
10.1002/hed.21027