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- Title
Increased expression of nuclear factor E2 p45-related factor 2 (NRF2) in head and neck squamous cell carcinomas.
- Authors
Stacy, Donnie R; Ely, Kim; Massion, Pierre P; Yarbrough, Wendell G; Hallahan, Dennis E; Sekhar, Konjeti R; Freeman, Michael L
- Abstract
Head and neck squamous cell carcinoma (HNSCC) continues to cause significant morbidity and mortality. Overexpression of specific phase II gene products may represent an important biomarker. One regulator of phase II gene expression is the transcription factor nuclear factor E2 p45-related factor 2 (Nrf2). Nrf2 expression was evaluated in HNSCC, to determine whether it might serve as a biomarker for early detection of disease.
- Publication
Head & neck, 2006, Vol 28, Issue 9, p813
- ISSN
1043-3074
- Publication type
Journal Article
- DOI
10.1002/hed.20430