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- Title
Determining the minimum clinically important differences for outcomes in the DOMINO trial.
- Authors
Howard, Robert; Phillips, Patrick; Johnson, Tony; O'Brien, John; Sheehan, Bart; Lindesay, James; Bentham, Peter; Burns, Alistair; Ballard, Clive; Holmes, Clive; McKeith, Ian; Barber, Robert; Dening, Tom; Ritchie, Craig; Jones, Rob; Baldwin, Ashley; Passmore, Peter; Findlay, David; Hughes, Alan; Macharouthu, Ajay; Banerjee, Sube; Jones, Roy; Knapp, Martin; Brown, Richard G; Jacoby, Robin; Adams, Jessica; Griffin, Mary; Gray, Richard
- Abstract
Although less likely to be reported in clinical trials than expressions of the statistical significance of differences in outcomes, whether or not a treatment has delivered a specified minimum clinically important difference (MCID) is also relevant to patients and their caregivers and doctors. Many dementia treatment randomised controlled trials (RCTs) have not reported MCIDs and, where they have been done, observed differences have not reached these.
- Publication
International journal of geriatric psychiatry, 2011, Vol 26, Issue 8, p812
- ISSN
1099-1166
- Publication type
Journal Article
- DOI
10.1002/gps.2607