We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Effectiveness of melatonin treatment on circadian rhythm disturbances in dementia. Are there implications for delirium? A systematic review.
- Authors
de Jonghe, A; Korevaar, J C; van Munster, B C; de Rooij, S E
- Abstract
Circadian rhythm disturbances, like sundowning, are seen in dementia. Because the circadian rhythm is regulated by the biological clock, melatonin might be effective in the treatment of these disturbances. We systematically studied the effect of melatonin treatment in patients with dementia. In addition, we elaborate on the possible effects one might expect of melatonin treatment in patients with delirium, since dementia and delirium are strongly related. Moreover, some evidence exists that sundowning in patients with dementia and the alterations in the sleep/wake cycle, seen in patients with delirium both originate from circadian rhythm disturbances.
- Publication
International journal of geriatric psychiatry, 2010, Vol 25, Issue 12, p1201
- ISSN
1099-1166
- Publication type
Journal Article
- DOI
10.1002/gps.2454