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- Title
Just how conserved is vertebrate sex determination?
- Authors
Cutting, Andrew; Chue, Justin; Smith, Craig A
- Abstract
Sex determination in vertebrate embryos has long been equated with gonadal differentiation into testes or ovaries. This view has been challenged over the years by reports of somatic sexual dimorphisms pre-dating gonadal sex differentiation. The recent finding that sex determination in birds is likely to be partly cell autonomous has again called for a broader definition of sex determination. Inherent sexual differentiation in each and every cell may apply widely among vertebrates, and may involve more than one "master sex gene" on a sex chromosome. At the gonadal level, key genes required for proper sexual differentiation are conserved among vertebrates, but their relative positions in the ovarian and testicular cascades differ.
- Publication
Developmental dynamics : an official publication of the American Association of Anatomists, 2013, Vol 242, Issue 4, p380
- ISSN
1097-0177
- Publication type
Journal Article
- DOI
10.1002/dvdy.23944