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- Title
Pilot study of the clinical and cognitive effects of high-frequency magnetic seizure therapy in major depressive disorder.
- Authors
Fitzgerald, Paul B; Hoy, Kate E; Herring, Sally E; Clinton, Anne Maree; Downey, Glenn; Daskalakis, Zafiris J
- Abstract
Electroconvulsive therapy (ECT) is a very commonly used treatment for patients with severe and treatment-resistant depression. Although effective, this treatment is complicated by a number of side effects including cognitive impairment motivating attempts to develop treatment alternatives. Magnetic seizure therapy (MST) is a brain stimulation technique using a high-powered transcranial magnetic stimulation device to produce therapeutic seizures. Preliminary research suggests that MST has antidepressant activity in the absence of cognitive side effects. The aim of this study was therefore to investigate the therapeutic efficacy and cognitive profile of MST provided at high frequency (100 Hz) and potentially longer stimulation trains and longer treatment courses than have been previously investigated.
- Publication
Depression and anxiety, 2013, Vol 30, Issue 2, p129
- ISSN
1520-6394
- Publication type
Journal Article
- DOI
10.1002/da.22005