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- Title
Serotonin transporter length polymorphism, childhood maltreatment, and chronic depression: a specific gene-environment interaction.
- Authors
Brown, George W; Ban, Maria; Craig, Thomas K J; Harris, Tirril O; Herbert, Joe; Uher, Rudolf
- Abstract
Key questions about the interaction between the serotonin transporter length polymorphism (5-HTTLPR) and stress in the etiology of depression remain unresolved. We test the hypotheses that the interaction is restricted to childhood maltreatment (as opposed to stressful events in adulthood), and leads to chronic depressive episodes (as opposed to any onset of depression), using gold-standard assessments of childhood maltreatment, severe life events, chronic depression, and new depressive onsets.
- Publication
Depression and anxiety, 2013, Vol 30, Issue 1, p5
- ISSN
1520-6394
- Publication type
Journal Article
- DOI
10.1002/da.21982