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- Title
Serotonin polymorphisms and posttraumatic stress disorder in a trauma exposed African American population.
- Authors
Mellman, Thomas A; Alim, Tanya; Brown, Denver D; Gorodetsky, Elena; Buzas, Beata; Lawson, William B; Goldman, David; Charney, Dennis S
- Abstract
Genetic polymorphisms that influence serotonin (5-hydroxytryptamine, 5HT) neurotransmission are candidates for contributing to susceptibility to posttraumatic stress disorder (PTSD). The objective of our study was to determine if a variable length polymorphism for the promoter regions of the 5HT transporter (5HTTLPR), and/or a substitution polymorphism in the promoter region for the 5HT2A receptor, would be associated with PTSD in a trauma exposed population of adult African-Americans.
- Publication
Depression and anxiety, 2009, Vol 26, Issue 11, p993
- ISSN
1520-6394
- Publication type
Journal Article
- DOI
10.1002/da.20627